Steroids and derivatives
Medchemexpress LLC Menadione-d3 | 5172-16-7 | 99.1% | 25 MG
Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo. It is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 10MG
GPI-1046 is a non-immunosuppressive immunophilin ligand used in research for its neuroprotective effects. It has been reported to upregulate glutamate transporter 1 (GLT1), reduce ethanol intake, and attenuate HIV-associated sensory neuropathy by modulating store-operated calcium entry. The compound is provided as a high-purity liquid (formula C20H28N2O4, MW ~360.45 g/mol).
- Non-immunosuppressive immunophilin ligand
- Reported neuroprotective activity
- Upregulates glutamate transporter 1 (GLT1)
- Attenuates HIV-associated sensory neuropathy via store-operated calcium entry modulation
- High purity (≈99.8%)
- Liquid appearance: colorless to light yellow
- Chemical formula C20H28N2O4; molecular weight ~360.45 g/mol
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month)
Medchemexpress LLC 1α,25-dihydroxy-3-epi-vitamin D3 | 61476-45-7 | MFCD28963706 | 98.5% | 416.64 g/mol | C27H44O3 | 1 MG
(1S)-Calcitriol is the 1S stereoisomer of calcitriol, a biologically active vitamin D metabolite that functions as a vitamin D receptor (VDR) agonist. Supplied as a solid research reagent, it is intended for in vitro studies of vitamin D signaling and nuclear receptor biology. The product includes storage and solubility guidance to maintain compound integrity.
- Acts as a vitamin D receptor (VDR) agonist for mechanistic studies.
- High purity suitable for in vitro assays.
- Recommended solubility in DMSO for stock preparations.
- Stable as a solid when stored protected from light at 4°C.
- Available in small solid pack sizes for research use.
Medchemexpress LLC Ofloxacin-d3 | 1173147-91-5 | 99.8% | 1 MG
Ofloxacin-d3 is a deuterium-labeled form of Ofloxacin designed for research applications. It serves as a tracer and an internal standard, facilitating quantitative analysis in methods like NMR, GC-MS, or LC-MS. This compound leverages stable heavy isotopes, which are incorporated into drug molecules to aid quantitation during drug development and may influence pharmacokinetic and metabolic profiles.
- Deuterium labeled Ofloxacin.
- Intended for research use only.
- Functions as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Estradiol/BSA | 95.0% | 1 MG
Estradiol/BSA is an antigen-adjuvant conjugate formed by coupling Estradiol with Bovine Serum Albumin (BSA). This conjugate is designed to enhance the production of antigen-specific antibodies in vaccine models by coupling the antigen with a protein adjuvant. It does not affect protein folding or disrupt major epitopes and can enhance cross-presentation and the generation of antigen-specific T cells. This product is for research use only.
- Enhances production of antigen-specific antibodies
- Used in vaccine models
- Does not affect protein folding
- Does not disrupt major epitopes
- Enhances cross-presentation
- Generates antigen-specific T cells
- Antigen-adjuvant conjugate
Santa Cruz Biotechnology β-Estradiol 3-sulfate sodium salt, 25 mg | CAS# 4999-79-5
β-Estradiol 3-sulfate sodium salt functions as a steroid hormone and exhibits estrogenic activity. It acts by binding to estrogen receptors, estrogen receptor alpha and beta, within the cell nucleus. This binding initiates a cascade of molecular events, leading to the regulation of gene expression and the modulation of various cellular processes. β-Estradiol 3-sulfate sodium salt′s mechanism of action involves influencing the transcription of target genes, thereby impacting the physiological responses of the cells. By interacting with estrogen receptors, β-Estradiol 3-sulfate sodium salt plays a role in the regulation of cell proliferation, differentiation, and apoptosis. Its activity at the molecular level contributes to the modulation of various signaling pathways and cellular functions, making it a relevant component in studies exploring hormone signaling and related biological processes.
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Selleck Chemical LLC Estradiol Cypionate S4046-50mg
Estradiol cypionate is the 17 -cyclopentylpropinate ester of estradiol which inhibits ET-1 synthesis via estrogen receptor
Apexbio Technology LLC Mifepristone, 100mg. Cas: 84371-65-3 MFCD: MFCD00867226. Progesterone receptor antagonist
Mifepristone (RU486) is a potent antagonist of progesterone receptor, used as a contraceptive agent. 84371-65-3. MFCD00867226
Apexbio Technology LLC Cyproterone Acetate 427-51-0 250mg
Cyproterone Acetate (CAS 427-51-0) is a small-molecule antagonist targeting the androgen receptor (AR) It is designed to inhibit AR activation thereby suppressing androgen-mediated cellular signaling Cyproterone Acetate exerts its biological activity primarily through competitive binding to AR displacing endogenous androgen ligands and blocking receptor activation and downstream signaling In experimental assays Cyproterone Acetate demonstrates AR inhibition with an IC50 value of approximately 7 1 nM At higher concentrations (EC50 around 4 0 M) it may also exhibit partial agonist activity on the AR pathway Based on these pharmacological properties Cyproterone Acetate holds research potential in studies of androgen-dependent biological processes AR signaling mechanisms and hormone-sensitive pathologies such as prostate cancer or androgen-related metabolic conditions
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Medchemexpress LLC Cortisone | 53-06-5 | 99.3% | 360.44 | 1 ML
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is an oxidized metabolite of Cortisol, a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in the binding of Glucocorticoid to the Glucocorticoid-receptor at high concentrations, and has been shown to attenuate apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) and decrease BCG lesions and tuberculin reactions in rabbits.
- Acts as an immunosuppressant
- Acts as an anti-inflammatory agent
- Attenuates apoptosis
- Decreases BCG lesions and tuberculin reactions
- Targets Glucocorticoid Receptor
- Is an endogenous metabolite
Medchemexpress LLC Hydrocortisone (Standard) | 50-23-7 | 362.46 | 100 MG
Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
- Analytical standard
- Intended for research and analytical applications
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
- Steroid hormone or glucocorticoid secreted by the adrenal cortex